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Flibanserin is an agonist of one of the serotonin receptors (5 - HT1A) and an antagonist at receptor 5 - HT2A. It is not known exactly how Flibanserin produces the sexual desire response but it is believed to involve a rebalancing of certain neurotransmitters in the brain related to inhibitory and excitatory responses, thereby producing a "normalization" of sexual desire.

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